Kirihito Sanka
Ode to Kirihito

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Older manga with the main characters being doctors who perform their duties as doctors ethically correct, trying to solve the misdeeds by the doctors who don't really care for sick people some way. Sometimes it really can get dark (not gore, but psychological). 

The main characters (and others in the surroundings) undergo a transformation that turns their whole life upside down. They suddenly hunger for meat that normal humans wouldn't eat. <>Tokyo Ghoul: ghouls can disguise themselves better than Monmow disease patients, because the whole faces of the patients in the latter group have become more dog-like. 

The two main characters are exposed to a certain ore or liquid that leads to their bodies getting malfunctions, leading to their eventual deaths, but not before turning them into a being that is completely pushed away from other humans. *The psychological aspect is great in both, but because Blue Phobia is a one-shot, that one could have been deeper.  

Something that had nothing to do with the protagonists of these stories, made them into some being that disgusted normal humans and made them want to stay away. However, both being doctors, they did not resent them, instead they spread good will: they comforted some and saved others. 

The main characters in these manga have undergone a change in their bodies due to certain doctors who think they can cover it all up, but they are gravely mistaken. The victim's life has been screwed totally. <>Heads: the procedure was vital to save his life, Kirihito Sanka: purely out of spite 

In both mangas main protagonists are doctors that have been cut off from the society and are trying to clear their names.  

Both works feature "freak shows" and people getting rejected by society for their appearance 

Medical-drama manga created to criticize the Japanese medical society. They are quite cynical, and do not mind touching upon sensitive and taboo subjects to get the message across. The protagonist is designed to be a good and morally-just doctor who goes to extreme lengths for the sake of his patients and refuses to back down in the face of the (exaggeratedly) corrupt and immoral community of doctors around him. The main difference is that Kirihito Sanka has supernatural elements while BJnY is grounded in reality. 

Both of these are darker "Gegika" works from master manga creator Osamu Tezuka. Both feature psychological story lines about the dark side of humanity.