Magan to Dangan wo Tsukatte Isekai wo Buchinuku!
Shoot Through a Different World with Magical Eyes and Bullets!

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Human Protagonist's Female Lead, or the Female protagonist herself is a Beastkin in fantasy/isekai. 'Beastkin' includes cat, wolf, rabbit, and others with fluffy ears and tails. This list is only for characters closely resembling a human other than the ears and tails. Also Beastman/Beastmen.

(PART 2) https://myanimelist.net/stacks/57034

Has a Female Lead of a Human-like Race/Creature in fantasy/isekai
https://myanimelist.net/stacks/38185
Protagonist becomes a non-human in fantasy/isekai
https://myanimelist.net/stacks/37527
Romantic Development with Monster Girl Female Leads/Heroines
https://myanimelist.net/stacks/36952

Adventurer party/Hero's Party in fantasy/isekai
https://myanimelist.net/stacks/36966

Has a Female Lead of a Human-like Race/Creature in Modern Setting on Earth
https://myanimelist.net/stacks/47294

Characters that look human but also have distinct features (eg. Animal Ears, Horns, etc.)

Since I've had trouble finding it myself, here's the collection of manga where the main character(s) have the advantage over the Sword and Sorcery world by flexing the most powerful magic of all: GUN.

Not saying they're all good, but I just want to collect as many in one place as I can.