The world is full of weird, supernatural, and--well frankly--out of this world illness that can not be described by modern medical practice. Depending on how the illness becomes, there may be many suggestions as to how it would be stuck to a person (namely curse).
This Anime does its job describing the origin of 'mysterious illness' and shows how humans deal with it while at the end of the day you can truly only cure it of the root cause. It is a causality rule which humans often forget exist.
to be honest, it really isn't something to be proud of, good enough art, good enough sound,
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