@ropiel Ok Here's a real answer to your question. I have read a fair bit of the Kusuriya no Hitorigoto novel and I've watched the show. I've read up to volume 6 or 7 (out of 8 so far) of the Raise wa Tanin ga Ii manga so I can give a rough comparison.
I thought the Kusuriya anime did a great job, but they also did a slightly better job of pacing in the anime than the novel did. A novel has a lot of content they can afford to edit out or change as long as you have a good director/writers. Plus a novel assumes you are going to sit down and read it from start to finish (or at least in chunks) so it can support a more complex story line. So you are starting from a slightly higher bar imo.
Raise wa Tanin ga Ii has released 8 volumes over 7 years. Assuming you are reading each volume 1 year apart (or in the serialized magazine however often it is released) the pacing is completely different. Even if a manga has a high page count, a lot of the space is filled with illustrations rather than dialogue. Basically, Raise wa Tanin ga Ii has a shallower story line. You can expect a richer visual experience, but a less fleshed out story line. This is where it's all going to be up to the production company to fill the gap. How will they do? We will have to find out. So far the first episode has followed the manga ok. They've done the humor well, but I am a bit iffy on the dramatic parts. Kirishima is supposed to flip from pretty normal to fairly creepy with a flip of a switch. The manga captures the atmosphere well in still frames, but the anime makes the moments feel more sleazy than dangerous to me. Yoshino is supposed to feel kind of Imperial when she snaps. Looking at people's comments, they seems to have liked her reaction, but I am not sure it conveyed her sense of absolute contempt as well as it could have.
I absolutely loved the manga the first time reading it, but I was reading it as it was released so there were long gaps between readings. I reread some of the manga just a few days ago in 1 sitting and since I knew the twists and gimmicks already it wasn't as exciting, but it was decent. Some of the emotional tension was drawn out for too long imo, but that's something the anime can address through editing and pacing. So fingers crossed the production team can pull it off.