 If you liked
Hanayome wa Motodanshi.
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 ...then you might like
Umareru Seibetsu wo Machigaeta!
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Both are autobiographical manga that deal with Sex Reassignment Surgery done in Thailand. (male to female)
Hanayome wa Motodanshi. focuses more on the relationship part of husband and wife, while Umareru Seibetsu wo Machigaeta! deals mainly with the SRS and healing process.
Both try to educate about a serious topic in a light-hearted and partially comedic matter.