 If you liked
Honzuki no Gekokujou: Shisho ni Naru Tame ni wa Shudan wo Erandeiraremasen Dai 1-bu - Hon ga Nai nara Tsukureba Ii!
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 ...then you might like
Kusuriya no Hitorigoto
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Myne is a passionate bookworm and Mao Mao is crazy about medicines and poisons. Myne causes a lot more mayhem with her love of books and Mao Mao is more grounded and does her best to "do no harm" with her knowledge (but she's still a pretty crazy mad scientist type). Both are great for a laugh and I highly recommend them. Both female leads are very clever and fun to watch in action. If you love one, you'll love the other.
The 2 of them have female leads with a very specific passion, one is book the other is medicine they take place in different setting, Kusuriya takes place in China.
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Recommended by Thereisnoonehere