 If you liked
Hana yori Dango
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 ...then you might like
Cat Street
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Both HYD and Cat Street are by Kamio Yoko. While their story and plot lines are different, the character interations are very similar, as well as overall plot development. In addition to that, her character styles are very similar. If you like the art and humor of HYD or CS, then you would like the other as well.
The actual plot of these two mangas are not that similar, but they do bear several similarities in what I think are the most important aspects. They are both about a unique girl (main character), a special school, and a group of close friends.
They are both sweet romances and full of humour. They will hold your attention your whole way through and have very nice drawing style (they are by the same authour). When I was reading them I just could not put them down!