 If you liked
NHK ni Youkoso!
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 ...then you might like
Nande Ikiteru ka Wakaranai Hito Izumi Sumi 25-sai
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Both manga focuses on the daily life of the MC who is experiencing depression, showcasing its negative influence, and providing indirect hints to overcome it, not only through the means of external intervention by other characters, but also through their inner monologues of feelings of anxiety, regrets and epiphanies.
These series capture how depression and anxiety feel better than most series I've read or seen. The uncertainty, nervousness, and guilt that people feel when they deal with depression/anxiety is portrayed in a realistic way. If Tatsuhiro Satou and Misaki Nakahara from Welcome to the NHK were relatable for you, Sumi Izumi from She Doesn't Know Why She Lives might be as well.
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