 If you liked
Saiunkoku Monogatari
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 ...then you might like
Kusuriya no Hitorigoto
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Akin to Ancient Chinese Imperial period stories, both of these shows are set in a fictitious Imperial palace setting where the female protagonists are sent to the royal imperial court (much to their dismay) in order to help resolve some of the internal, societal & political problems the kingdom is facing.
Shuurei & Maomao (respectively) are both geniuses & savvy in their own right and carry themselves as they navigate through imperial life. It's rather imperative that audiences must have some knowledge in imperial royal & political systems to fully appreciate the world building of both shows.
both heroines are hired to court in ancient china (saiunkoku resembles china at least) and have close relations to someone of noble origin hiding their identity. they both come from wealthy families but live in modest circumstances. they are incredibly talented and knowledgable, insastiably curious and borderline obsessive. they tackle and resolve matters of national importance and find themselves in the center of all kinds of palace intrigues, power struggles etc. all subplots are important for the main plot.
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Recommended by Asbjoernson
Wanted to know what a grounded Chinese court drama would look like in anime format? Well, here you go....
In a fictional kingdom clearly inspired by Imperial China, a young, unassuming girl gets to work at the Imperial Palace. However, our heroine is soon implicated into a world of conspiracy and intrigue. She has to rely on her wits and skills to navigate the treacherous waters of the Imperial court.
Despite their seemingly serious setup, both Saiunkoku Monogatari and The Apothecary Diaries also feature lighthearted storybeats and moments of levity that help prevent the experience from becoming a dour bore.
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Recommended by Alpha-Nine
both has same settings. MC is from a poor family but with respectable background and for difference reason have to work at the palace. then SC which is higher up, interested in her because of her capability. both MC also has to solve problem altough with different bacground. kusuriya using medicine while sainkoku using common knowledge.
when watching the first episode of kusuriya, i was striked by the same settings. this makes me want to watch saiunkoku again.