 If you liked
Freezing
|
 ...then you might like
Hundred
|
A battle school harem series with an strong superhuman threat to humanity.
Also features a very diverse cast of female characters.
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Recommended by Mysteriala
Both shows consist of characters using materialized weapons to kill alien invaders by destroying their cores. They also both have a locked away "patient 0" that has been changed in someway from their interaction with the alien invaders and researching this change is what allowed the characters to create the weapons they use to fight off the alien species.
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Recommended by AndroidRoberts