If you liked
Kidou Senshi Gundam SEED
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...then you might like
Kidou Senshi Gundam: Tekketsu no Orphans
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Like SEED, discrimination against human beings who are not "natural" is a common theme because in both of these series non-natural human beings are so prominent unlike the emergent NewTypes, Innovators and X-Rounders.
In SEED, genetically engineered human beings called Coodinators dominate the space colonies, whereas on Earth, especially in member-nations of the Alliance, Coordinators are referred to as monsters. The discrimination is field by the propaganda of terrorist organization Blue Cosmos who influence nations in the Alliance.
In G-Tekketsu, people who have prosthetics, whether it be the highly advanced Alaya-Vijnana system or something so basic as artificial legs, are also referred to as monsters or
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Recommended by Fortress_Maximus
Both plots rely heavily on a "racism" theme as well as changing government and civilian rights. There is also the concept of people "made" to control Mobile Suits. The only difference is that Iron-Blooded Orphans has less action (as in they don't fight in every single episode). But when there is no fighting they are forwarding characterization and introducing new plot pieces.
All in all, Iron-Blooded Orphans reminds me of Seed a lot! It's definitely worth a try :D