 If you liked
Appleseed (Movie)
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 ...then you might like
Vexille: 2077 Nihon Sakoku
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They both have similar animation, futuristic setting, a female main character, and both have androids (robots, bio-bots etc).
Both by the same producer and explores the notion of bio engineered humans and other such possibilities. Although, Vexille is slightly more about the ethics of such research and experimentation. But both are equally good movies.
Both are fully CG animated scifi action movies, with very similar settings (like mech-suits and both main protagonists are members of a special units). And both stories are fairly straight forward and entertaining scifi-romp, without too much pointeless philosophy or thought.
Visually it looks the same and even the plots are kind of similar. Vexille is a lot more "gritty" in the setting though.
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Recommended by outlawvenom
Both about a post apocalyptic world.Has similar themes through out the story. CGI anime.
I don't want to put to much in case I spoil something. But go check out them out.
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Recommended by InuyashaSit
Deunan Knute and Vexille are both young, pretty and athletic type ladies. They both take place in futuristic settings and the stories in both those animes involve androids and advanced armor used in combat. The director of Vexille, Fumihiko Sori, and the writer of Vexille, Haruka Handa, both worked on Appleseed.
Also, they both have great action sequences (even though I think Appleseed had better ones), great looking CG and music artists like Paul Oakenfield, Boom Boom Satellites and Basement Jaxx both were part of the soundtracks for both animes.
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Recommended by Nerdszrule89