If you liked
Heppoko Jikken Animation Excel♥Saga
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...then you might like
Lucky☆Star
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Crazy Parodies ^^ (also, Lucky Star parodies Excel Saga once or twice xD)
Both have the same random, comical quality. Both are over-the-top and obnoxious. Both have the overly excited female main characters. Both make no sense. If you enjoyed one, you need to see the other.