 If you liked
Blood+
|
 ...then you might like
Kyuuketsuhime Miyu (TV)
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a girl and her companions fight monsters (technically her own kind). both vampires.
Saya~Miyu
Haji~Lava
Chiropteran~Shinma
Diva~Chisato
They both deal with vampire/demon like main characters who's mission is to destroy an evil race that is plaguing human society. The main characters both love their "helpers" but feel that it is impossible to be in a relationship with them.
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Recommended by Taylorgg12