 If you liked
Urusei Yatsura
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 ...then you might like
Doraemon (2005)
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There are many elements that make both series comparable.
Structurally these two anime don't follow much of an overarching plot and most of the episodes revolve around the MC fiddling with aliens and their technology (Lum) or future gadgets (Doraemon) and most of the time ending with unfavorable results since they're both so alike and unlucky. It's also worth noting that the two MCs also have a bad reputation in their respective series and no one places much hope in neither of them.
You can feel a bit of an evolution of Ataru's love feelings in Urusei Yatsura while in Nobita's case he's always back and
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