 If you liked
Fullmetal Alchemist
|
 ...then you might like
Karneval (TV)
|
In both these anime, there are creepy apparently soulless creatures that are difficult to defeat: the Varuga from Karneval and the Homunculus-type creatures from Fullmetal Alchemist. Also, in both anime, there is a strong bond between the two main characters and a tendency to go from bright and cheerful to very dark.
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Recommended by shadowfireflame