 If you liked
Uchuu Kaizoku Captain Herlock
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 ...then you might like
Black Jack
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A three-words review for both: screw the system.
The dark, handsome and stoic titular anti-heroes have scarred faces, strong morals and no bounds in acting illegally to halt big powers' greed and corruption: Harlock as a space pirate, Hazama as an unlicensed doctor. Many individuals who meet or join them end up admiring and following their revolutionary mindset and visionary charme, while inside their (very hard to break) shell lies actual heart and compassion - especially with their crewmates/clients and little adoptive daughters-sidekicks.
(Un)arguably the most based and iconic characters/works of their famed authors, they are the best possible start to get familiar with Tezuka and Matsumoto.
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Recommended by RenaPsychoKiller
They depict a gruff, black-cloaked, scar-faced man and his thrilling life as an outcast from the law. Appearances aside, he has a strong moral code and sense of justice that inspires people that he meets and encourages them to pursue their dreams. The protagonist dislikes the greedy bigwigs who plague the medical society and government, and makes a point of giving them a hard time through their extra-legal endeavours. The protagonist also acts as the Guardian and father figure to a little girl who he is not related to by blood.