After Ginko was orphaned by a landslide she took him in and cared for him. She taught him about the Mushi, but harbored a secret from him.
The Mushi in the pond near where she lives are responsible for her hair color turning white and the loss of her eye. When the other eye is lost over time the person who is afflicted turns into a shadow where they are consumed and swept away by the great Ginko mushi that lives in the pond alongside the darkness mushi.
She is a Mushi master and has lost her hair color and right eye to the Mushi living in the pond near her house.
She can be heard narrating some of the opening and closing lines of the anime.