Blue Seed

Both deal with supernatural creatures and mythology. There are also similarities in the female leads, both have high spiritual energy and are high school girls that grew up in temples. There is also the connection of the male leads, both are only half human, in love with someone that looks just like the female lead, act like punks but are truly kind hearted and value friendship.  

Basically, Kusanagi is Inuyasha and Momiji is Kagome. Katy (or Kaede) is Kikyo. Silly love triangle and "Collect the Shikon Jewel/Mitama!" plotline included for free! 

Well,Both animes have same genres of Action, Horror, Demons, Romance ect. I think Inuyasha is much better than Blue Seed, only because Kagome doesnt scream as much as Momiji does from Blue Seed but both girls are in Middle school when they find out about demons n choose to fight them with friends, they both have special powers of a Priestess they have inherited from pervious ancestors, they both fall in love with a half demon, half human boy who fights to protect them, though not at first, both half demons had previous loves that have ties to each girl's past (With Inuyasha, he was in love with Kagome's past life Kikiyo n in Blue Seed, he fell in love with Momiji's older twin sister) they are very similar so if you liked one, you might like the other read more 

Blue Seed and Inuyasha are VERY similar, and I've even heard that Inuyasha was based on Blue Seed, though I haven't verified this. For starters, the characters in each show have their counterparts in the other, like Inuyasha is Kusanagi's counterpart and Momiji is Kagome's. The parallels between the two series are easily visible, from characters to plot points to setting. Inuyasha takes place in Japan's feudal era, and Blue Seed is centered around ancient Japan. In both series the characters fight demons. They each have different and valuable lessons to be learned from watching them, so I recommend you check both out.  

Both anime has a girl who is needed to defeat evil and there is a man that isn't human that protects the girl. For both guys, they were both in love with a different girl who was close to the main girl now (Kikyo in Inuyasha and Kaede in Blue Seed). 

Both focus on the main character's "destiny" as a protector (Pretear- Himeno as the Pretear; Blue Seed- Momiji as the Kushinada). Also, both shows' enemies are created by evil seeds that are put into objects and turn the objects into evil creatures. Both anime are very good and an excellent watch! :)