Blade

Dante and Blade are hybrid of two different races, rather it would be demon and human or vampire and human. Their job? To hunt down and kill the demon/ vampire race that preys on human. There will be violence and lots of it, along with action. 

Both anime have a very similar plot which involves a badass superhuman tracking someone down who leads an organisation that produces monstrous beings. So, if your a big fan of a chase that involves a lot of action and monsters I suggest you go watch one of these. 

Both main characters are half human, half vampires in quest against all vampires. 

Same animation style Story about a man on the hunt for a specific person who wronged them Shared timeline due to Wolverines appearance in Blade anime Both have good action and decent adventure aspects  

+Both have human experiments. +Both main characters have sad past. +Both have similar atmosphere,animation and plot .  

Vampires killing vampires is the key aspect both series share. In addition to that both Alucard and Blade fights for the sake of a human being, and dedicate their life for accomplishing that goal of theirs. Action pack, violent, gory, what else can i say... 

Action-oriented series with a black protagonist who is talented in sword combat. Both Afro and Blade are hunting the person responsible for the death of a family member. They also carry a special memento that will eventually be helpful during their quest.