Shinmai Renkinjutsushi no Tenpo Keiei

1) Both animes are following the MC's as they build a store to help those around them. So following a lot of their day to day lives as owners and the troubles that arises around them. Both in relation to their business' and personal lives. 2) Both MC's show talent/power greater than those around them that they both use to help further their craft and talents. 3) Both MC's generally want to help people out of the generosity of their hearts, but Shinmai's MC isn't afraid to get that money while doing so. I know that's similar to point 1, but I think it's different enough. 

- light slice of life anime - op mc - great friendship  

Both Escha and Sarasa travel to another city for working as a alchemists 

- Both MC's are cute girls trying to run a shop in a fantasy world, and are concerned with money. - Both MC's are capitalistic, intelligent, a little schemie but with a heart in the right place, and have no reservations when it comes to self-defense against bandits. - Both involve economics, business practices and partners, and the problems of rival competition, and scammers. - Both show the improvement of the quality of life for the local residents due to the MC's business. - Both MC's attract the attention of the local governments, and start coordinating with them. - Both MC's attract cute girls who befriends them, and are cute. - Both MC's hire adventurers desperately looking for work to help with her business, and they become her friends. - Don't mess with either MC, they'll wreck you. Both had people who tried to mess with the MC's and got wrecked.  read more 

The premise of these two anime is to create items using alchemy. Both stars female MCs.